A non-hallucinogenic version of the psychedelic drug ibogaine, with potential for treating addiction, depression and other psychiatric disorders, has been developed by researchers at the University of California, Davis.
Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings of the National Academy of Sciences, the work could lead to diagnostic tests and new therapies to slow or stop the spread of cancers.
Technologies developed at UC Davis enabled the foundation of 14 startup companies during the fiscal year ending June 30, 2019. Two of the startups were founded by faculty in the College of Letters and Science.
A synthetic, non-intoxicating analogue of cannabidiol (CBD) is effective in treating seizures in rats, according to research by chemists at the University of California, Davis. The synthetic CBD alternative is easier to purify than a plant extract, eliminates the need to use agricultural land for hemp cultivation, and could avoid legal complications with cannabis-related products.
Metals such as zinc, copper and chromium bind to and influence a peptide involved in insulin production, according to new work from chemists at the University of California, Davis. The research is part of a new field of “metalloendocrinology” that takes a detailed look at the role of metals in biological processes in the body.
Although trace metals such as copper, zinc and cobalt play a pivotal role in human health, not much is known about how the body uses these elements. A better understanding of the role and influence of metals could lead to new biomarkers and diagnostic tests for metabolic disorders such as diabetes and nonalcoholic fatty liver disease (NAFLD), says UC Davis professor Marie Heffern, who specializes in bioinorganic chemistry.
The growing popularity of microdosing — taking tiny amounts of psychedelic drugs to boost mood and mental acuity — is based on anecdotal reports of its benefits. Now, a study in rats by researchers at the University of California, Davis, suggests microdosing can provide relief for symptoms of depression and anxiety, but also found potential negative effects.
A team of scientists at the University of California, Davis, is exploring how hallucinogenic drugs impact the structure and function of neurons — research that could lead to new treatments for depression, anxiety and related disorders.
Alexandra Greb, a UC Davis senior in pharmaceutical chemistry from Danville, California, is a co-author on a new study exploring how hallucinogenic drugs affect the structure and function of neurons. The research could lead to new treatments for depression, anxiety and related disorders.
Using a newly developed technique, researchers from Japan, Germany and UC Davis have identified a key step in production of hydrogen gas by a bacterial enzyme. Understanding these reactions could be important in developing a clean-fuel economy powered by hydrogen.
