Evidence from human and animal testing suggests the brain-altering effects of psychedelics could be repurposed for treating addiction. Now, researchers at University of California, Davis, and the University of Colorado Anschutz Medical Campus plan to screen hundreds of compounds to discover new, non-hallucinogenic treatments for substance use disorders.
Marie Heffern, assistant professor of chemistry, was awarded a prestigious CAREER grant from the National Science Foundation (NSF) this month. The NSF Faculty Early Career Development (CAREER) program funds junior faculty who perform outstanding research, are excellent educators and include outreach in their work. Heffern is the third faculty member in the UC Davis Department of Chemistry to receive a CAREER award in 2021.
A genetically encoded fluorescent sensor to detect hallucinogenic compounds has been developed by researchers at the University of California, Davis. Named psychLight, the sensor could be used in discovering new treatments for mental illness, in neuroscience research and to detect drugs of abuse.
A natural brilliant blue coloring has been discovered by an international team of researchers including chemists at the University of California, Davis.
A non-hallucinogenic version of the psychedelic drug ibogaine, with potential for treating addiction, depression and other psychiatric disorders, has been developed by researchers at the University of California, Davis.
Changes in a specific type of sugarlike molecule, or glycan, on the surface of cancer cells help them to spread into other tissues, according to researchers at the University of California, Davis. Published March 23 in Proceedings of the National Academy of Sciences, the work could lead to diagnostic tests and new therapies to slow or stop the spread of cancers.
Technologies developed at UC Davis enabled the foundation of 14 startup companies during the fiscal year ending June 30, 2019. Two of the startups were founded by faculty in the College of Letters and Science.
A synthetic, non-intoxicating analogue of cannabidiol (CBD) is effective in treating seizures in rats, according to research by chemists at the University of California, Davis. The synthetic CBD alternative is easier to purify than a plant extract, eliminates the need to use agricultural land for hemp cultivation, and could avoid legal complications with cannabis-related products.
Metals such as zinc, copper and chromium bind to and influence a peptide involved in insulin production, according to new work from chemists at the University of California, Davis. The research is part of a new field of “metalloendocrinology” that takes a detailed look at the role of metals in biological processes in the body.
Although trace metals such as copper, zinc and cobalt play a pivotal role in human health, not much is known about how the body uses these elements. A better understanding of the role and influence of metals could lead to new biomarkers and diagnostic tests for metabolic disorders such as diabetes and nonalcoholic fatty liver disease (NAFLD), says UC Davis professor Marie Heffern, who specializes in bioinorganic chemistry.
